Risk Assessment Tools

Hereditary Breast and Ovarian Cancer
Hereditary Nonpolyposis Colorectal Cancer

Hereditary Breast and Ovarian Cancer

Personal and family history increases the risk of hereditary breast and ovarian cancer. Mutations in the BRCA1 and BRCA2 genes are responsible for the majority of hereditary cases and can be inherited equally from the mother's or father's side of the family.Studies of high risk families have shown that for women with breast cancer caused by BRCA mutations, the risk of a second breast cancer in the opposite breast by age 70 is between 50% and 64%, and the risk of ovarian cancer is increased 10-fold. The ability to test for hereditary breast and ovarian cancer risk gives women and their relatives the opportunity to take steps to improve their healthcare. Recent studies show that drug therapies, surgical techniques and other options can significantly reduce the risk of breast and ovarian cancer in high-risk women.

The questionnaire may be used to collect and submit your information to your Tennessee Oncology physician. If you have one or more checks on this questionnaire, you should click the submit button and your physician will evaluate your hereditary risk of breast and ovarian cancer and will discuss this with you at your next scheduled appointment. You may also want to print a copy of this tool to take with you to your next appointment.

Please use this Breast and Ovarian Cancer Risk Assessment Tool to determine if you or a family member is at risk for these cancers.

Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

Colorectal and endometrial cancers can be indicators of an important hereditary cancer condition known as Hereditary Nonpolyposis Colorectal Cancer (HNPCC). HNPCC is the most common form of hereditary colon cancer and is responsible for 3-5% of all colorectal cancers.

Tennessee Oncology strives to increase the early detection of HNPCC and other cancers. With the use of the screening tools below and genetic tests like COLARIS™, Tennessee Oncology hopes to increase the early detection of HPNCC and other hereditary cancers. COLARIS™ is most appropriate for individuals who are likely to have HNPCC due to their personal and family history. COLARIS™ provides you with invaluable information to assist in preventing cancer. The benefits of HNPCC testing are as follows:

• Preventing cancer through appropriate interventions and procedures for accurately identified individuals with an HNPCC mutation carriers.
• Avoiding unnecessary interventions and procedures for family members who did not inherit the mutation.
• Providing an explanation of the underlying cause of cancer in individuals or family members.
• Defining your personal risks of developing an HNPCC related cancer.

Please use HNPCC Risk Assessment Tool to determine if you or a family member is at risk for HNPCC.

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